ACTIVE INGREDIENTS
Use in Biogreen Science Product

Phytocelltec™ ALP ROSE
PhytoCellTec™ Alp Rose is a cosmetic ingredient based on stem cells of alpine rose leaves.


The Alpine Rose
The alpine rose is a typical Swiss flowering plant from the Alps. It has bright pink blossoms and grows at altitudes up to 3200 m. Its evergreen leaves are especially resistant to high UV radiation and extreme dryness and cold. The sturdy leaves are a shiny green, even once the snow has melted in the spring. This phenomenon is due to the presence of a special protection protein called dehydrin in the leaves of the alpine rose.

Plant Stem Cells for Skin Stem Cells
The development of the innovative PhytoCellTec™ technology made it possible to grow plant stem cells on a large scale. It also became possible to effectively cultivate rare and endangered plants like the Uttwiler Spatlauber. PhytoCellTec™ made plant stem cells available for cosmetics for the first time.

The Effect
Mibelle Biochemistry was able to show in comprehensive studies that PhytoCellTec™ Malus Domestica, the active ingredient based on apple stem cells, promotes the vitality and longevity of skin stem cells, protects them from damage due to environmental stress, and thus delays the skin aging process.

Summary
PhytoCellTec™ Malus Domestica has opened up entirely new possibilities in the field of cosmetics. Using plant stem cells can slow skin aging by protecting essential skin stem cells, keeping the skin looking youthful longer, and giving it a better and more vital appearance.




Protects Epidermal Stem Cells from UV stress
Cultures of epidermal stem cells were treated with PhytoCellTec™ Alp Rose, while others were left untreated. The cultures were then exposed to UVA and UVB rays. The colony-forming efficiency (CFE) of the stem cells was then measured. The results showed that UV radiation strongly reduces the cells' colony-forming efficiency. Treatment with PhytoCellTec™ Alp Rose increased the stem cells' colony-forming efficiency (vitality) and provided significant protection against UV rays.
(see chart)





Ski Holiday Study
Twenty-two subjects were treated with an SPF 30 sunscreen formula during their ski holidays (1 week in March, Alps) to test the effect of PhytoCellTec™ Alp Rose in extreme environmental conditions. Sunscreen without the active ingredient was applied to one side of a subject's face, while the other side was treated with sunscreen containing the active ingredient PhytoCellTec™ Alp Rose. The loss of skin moisture in the face was then measured after another week of treatment at home. The results showed that water loss was reduced by 39% after 2 weeks' treatment with PhytoCellTec™ Alp Rose. This indicates that PhytoCellTec™ Alp Rose strengthens the skin barrier and makes it more resistant to environmental stresses such as UV, wind, cold temperatures and dryness. (see chart)
Source Mibelle Biochemistry